论文部分内容阅读
目的观察海珠区中小学接种甲型H1N1流行性感冒疫苗(简称甲流疫苗)的安全性和流行病学保护效果。方法采用描述流行病学、队列研究方法,对2116名接受甲流疫苗接种(接种组)和2762名未接受甲流疫苗接种(对照组)的在校中小学随访1年,观察甲型H1N1流感疫苗的安全性和流行病学保护效果。结果接种甲型H1N1流感疫苗师生中,累计报告不良反应人数为4例,报告率为189/10万,所有接种对象在接种后半年内未报告格林巴例综合征(GBS);接种组流感样病例发病率为3.2%,对照组发病率为4.5%,疫苗保护率为28.9%,保护效果指数为1.39。接种组甲流病例发病率为0.24%,对照组发病率为0.72%,疫苗保护率为67.37%,保护效果指数为3.06。结论甲型H1N1流感疫苗具有良好的安全性和较好的流行病学保护效果。
Objective To observe the safety and epidemiological protective effect of influenza A (H1N1) vaccination in primary and secondary schools in Haizhu District. Methods An epidemiological and cohort study was conducted to investigate the prevalence of Influenza A (H1N1) virus in 2116 school-aged primary and secondary schools for 1 year after being vaccinated (inoculation group) and 2,762 non-A flu vaccine recipients (control group) Vaccine safety and epidemiological protection. Results Among the teachers and students vaccinated with influenza A (H1N1) vaccine, the cumulative number of reported adverse reactions was 4 and the reported rate was 189/10 million. All vaccinated subjects did not report GBS within six months after inoculation. Inoculation group flu The incidence of such cases was 3.2%, the incidence of the control group was 4.5%, the vaccine protection rate was 28.9%, and the protection effect index was 1.39. Inoculation group a case of flow rate was 0.24%, the incidence of the control group was 0.72%, the vaccine protection rate was 67.37%, the protection effect index was 3.06. Conclusion Influenza A H1N1 influenza vaccine has good safety and good epidemiological protection.