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本文研究不同浓度乙酰胆碱（ＡＣｈ）对Ｔ淋巴细胞增殖的影响，并初步探讨Ｍ型胆碱能受体在ＡＣｈ调节Ｔ细胞增殖中的作用，结果表明：１０－１０ｍｏｌ／Ｌ浓度ＡＣｈ对Ｔ细胞增殖无明显影响，而１０－９～１０－４／ｍｏｌ／Ｌ浓度ＡＣｈ均可显著增强Ｔ细胞对刀豆素Ａ的增殖反应；其中以１０－７ｍｏｌ／Ｌ和１０－６ｍｏｌ／Ｌ两个ＡＣｈ浓度的作用最强。１０－６ｍｏｌ／Ｌ的阿托品可阻断１０－７ｍｏｌ／Ｌ的ＡＣｈ对Ｔ细胞增殖的影响。结果提示：ＡＣｈ在较大的浓度范围内均可促进细胞免疫功能，ＡＣｈ增强细胞免疫的作用可能是通过Ｍ型胆碱能受体实现的。
In this paper, the effects of different concentrations of acetylcholine (ACh) on the proliferation of T lymphocytes were studied, and the role of M-type cholinergic receptors in the regulation of T cell proliferation was investigated. The results showed that the proliferation of T cells was induced by ACh (10-10mol / L) No significant effect, while the concentration of 10-9 ~ 10-4 / mol / L ACh can significantly enhance the T cell proliferation response to concanavalin A; which 10-7mol / L and 10-6mol / L two ACh concentrations The strongest role. Atropine 10-6mol / L can block 10-7mol / L of ACh on T cell proliferation. The results suggest that: ACh can promote cellular immune function in a wide range of concentrations, ACh enhanced cellular immunity may be through the M type cholinergic receptors.