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作者试用海蒽酮1次肌肉注射治疗感染曼氏血吸虫病的小白鼠,企图在治疗后24小时左右获得促使虫体肝移的结果,但没有成功。实验鼠,每鼠经皮肤感染100条左右尾蚴,6周后分成2组,第1组用甲烷磺酸盐80毫克(基质)/公斤剂量,1次肌肉注射,药物溶解于含有25%Cremopher EL的0.85%盐水中。第2组小白鼠仅用溶媒治疗作为对照。从每组中各剖杀2～4只小鼠,用灌冲法
The authors tried a single intramuscular injection of haigenone to treat mice infected with schistosoma mansoni and attempted to obtain a result of promoting hepatic migration of the worms at about 24 hours after treatment, but this was unsuccessful. Rats were infected with 100 or so cercariae per mouse. Six weeks later, they were divided into two groups. The first group used methane sulfonate 80 mg (matrix)/kg dose, one intramuscular injection, and the drug dissolved in 25% Cremopher EL. 0.85% in salt water. Group 2 mice were treated with vehicle alone as a control. Two to four mice were sacrificed from each group and irrigated