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目的：分析血液灌流联合血液透析治疗慢性心肾综合征维持性透析患者顽固性低血压的临床疗效。方法回顾我院收治的慢性心肾综合征维持性透析合并顽固性低血压患者20例临床资料，对患者行血液灌流联合血液透析治疗。结果20例患者治疗12 w后低血压发生率15%较治疗前11 w发生率明显降低，治疗13 w SBP、DBP水平较治疗前增加明显，差异有统计学意义（P<0.05）。结论血液灌流联合血液透析治疗慢性心肾综合征维持性透析患者顽固性低血压临床效果显著，价值确切。“,”Objective To evaluate the clinical efficacy of hemoperfusion combined with hemodialysis in the treatment of refractory hypotension in maintenance dialysis patients with chronic cardiopulmonary syndrome. Methods The clinical data of 20 patients with chronic cardiopulmonary syndrome (CPD) and hemodialysis combined with hemodialysis were retrospectively reviewed. Results The incidence of hypotension after treatment for 12 weeks was significantly lower than that before treatment (P<0.05). The incidence of SBP and DBP increased significantly after treatment for 13 weeks (P <0.05). Conclusion Hemoperfusion combined with hemodialysis is effective in the treatment of refractory hypotension in chronic cardiopulmonary syndrome patients with maintenance hemodialysis.