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目的介绍多西紫杉醇联合化疗法治疗非小细胞肺癌的研究进展。方法通过查阅国内外的文献资料,讨论多西紫杉醇联合铂类制剂和非铂类第3代药物的临床疗效和不良反应。结果多西紫杉醇联合化疗法治疗非小细胞肺癌疗效确切、不良反应轻微。结论联合化疗方案有望解决单药方案有效率略低的问题,并为非小细胞肺癌的治疗提供临床指导。
Objective To introduce docetaxel combined with chemotherapy for the treatment of non-small cell lung cancer. Methods The clinical efficacy and adverse reactions of docetaxel in combination with platinum preparations and non-platinum third-generation drugs were discussed through consulting domestic and foreign literature. Results docetaxel combined with chemotherapy for the treatment of non-small cell lung cancer is effective and mild adverse reactions. Conclusion The combination chemotherapy is expected to solve the problem of slightly lower efficiency of single drug regimen and provide clinical guidance for the treatment of non-small cell lung cancer.