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目的探讨β-人绒毛膜促性腺激素(β-human chorionic gonadotropin,β-HCG)、孕酮(progesterone,P)对异位妊娠(ectopic pregnancy,EP)早期诊断的临床价值。方法回顾性分析2008~2012年柳州市第二妇幼保健院收治的50例EP患者(A组)的临床资料,与同期50例宫内妊娠孕妇(B组)相比较,观察两组间停经7周内与7周后的β-HCG、P水平的差异。通过ROC曲线分析确定EP的β-HCG、P临界值。结果停经7周内与7周后A组的β-HCG、P显著低于B组(P<0.05)。ROC曲线分析显示,β-HCG、P的临界值分别为5 321U/L、47 nmol/L时有较高的灵敏度和特异度。结论β-HCG与P对早期诊断EP有重要意义。
Objective To investigate the clinical value of β-human chorionic gonadotropin (β-HCG) and progesterone (P) in the early diagnosis of ectopic pregnancy (EP). Methods The clinical data of 50 cases of EP patients (Group A) admitted to the Second Maternal and Child Health Hospital of Liuzhou from 2008 to 2012 were retrospectively analyzed. Compared with 50 cases of pregnant women of intrauterine pregnancy (Group B) during the same period, Week and 7 weeks after the β-HCG, P level differences. The β-HCG, P threshold of EP was determined by ROC curve analysis. Results β-HCG and P in group A were significantly lower than those in group B (P <0.05) after 7 and 7 weeks after menopause. ROC curve analysis showed that the cut-off values of β-HCG and P were 5 321U / L and 47 nmol / L respectively, which had higher sensitivity and specificity. Conclusion β-HCG and P are of great significance in the early diagnosis of EP.