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百草枯(paraquat,1,1-二甲基-4,4-联吡啶阳离子盐),是目前应用最广泛的触灭型除草剂之一,动物属中等毒性,但对人的毒性却较高,成人估计致死量40mg/kg。百草枯中毒后可造成多个系统或器官损害,肺部最为严重,病死率极高,致病机制复杂且尚未完全明确,目前在治疗上仍无特效解毒药,多以综合治疗为主,本文就百草枯中毒的研究及治疗研究情况进行综述。
Paraquat (1,1-dimethyl-4,4-bipyridinium cation salt) is one of the most widely used hit-and-run herbicides. The animals are moderately toxic but have high toxicity to humans , Adult estimated lethal dose 40mg / kg. Paraquat poisoning can cause multiple system or organ damage, the most severe lungs, high mortality, pathogenic mechanism is complex and not yet fully clear, there is no effective antidote in the treatment, mostly combined treatment, this article Paraquat poisoning research and treatment of research situation are reviewed.