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作者为了测定结核性脑膜炎患者对维生素乙_1负荷试验,每天肌肉注(?)盐酸硫胺25毫克,连用三天。注射维生素乙_1后,须计算每昼夜尿中排出与注入维生素乙_1的百分比。被检查的大多数病人在负荷第一天排出大量维生素乙_1;在第三天维生素乙_1排泄量恢复正常。作者认为此种现象与肝脏对维生素乙_1的含磷化合物代谢过程障碍有关。在负荷第三天维生素乙_1恢复正常水平,作者认为这与维生素乙_1本身影响下具有高能含磷化合物代谢恢复有关。
In order to determine the test of vitamin B 1 in patients with tuberculous meningitis, the authors injected 25 mg of thiamine hydrochloride intramuscularly daily for three days. After injection of vitamin B 1, it is necessary to calculate the percentage of urine excreted and injected vitamin B 1 per day and night. The majority of patients examined were excreted in the first day of loading vitamin B-1; on the third day of vitamin B-1 excretion returned to normal. The authors believe that this phenomenon and the liver vitamin B-1 phosphorus-containing compounds related to metabolic disorders. On the third day of loading vitamin B-1 returned to normal levels, the authors believe that this is related to the metabolism of high-energy phosphorus-containing compounds under the influence of vitamin B-1 itself.