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中南大学湘雅医院刘瑛、肖献忠等用含 15 0 0 0个小鼠已知基因及ＥＳＴ片段的ｃＤＮＡ芯片从热休克因子1(ＨＳＦ1)基因敲除小鼠心肌组织中筛选应激反应中受ＨＳＦ1调控的靶基因 ,结果共筛选到差异表达基因114 2个。对上述基因的分析发现多个基因的启动子区含有热休克元件 (ｈｅ
Xiangya Hospital of Central South University, Liu Ying, Xiao Xianzhong and other containing 1500 cells known genes and EST fragments of cDNA chips from heat shock factor 1 (HSF1) knockout mice myocardial tissue screening stress response by HSF1 regulation of the target gene, a total of 114 differentially expressed genes were screened. Analysis of the above genes revealed that the promoter regions of multiple genes contain heat shock elements (He