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目的探讨阴道分娩时卡孕栓不同给药途径,预防产后出血的效果及不良反应。方法选取我院2013年5月至2014月6月1796例单胎妊娠正常阴道分娩初产妇随机分为舌下含化组、直肠用药组、阴道用药组,使用卡孕栓后观察产后2 h出血量及不良反应的发生。结果舌下含化组及直肠用药组产后2 h出血量减少,与阴道用药组比较,差异有统计学意义(P<0.05),阴道用药组不良反应最轻,直肠用药组发生腹泻的比例高于舌下含化组,预防应用卡孕栓1 mg较治疗应用卡孕栓2 mg不良反应轻,差异均有统计学意义(P<0.05)。结论胎儿娩出时舌下含化卡孕栓1 mg,用药方便,不良反应小。
Objective To investigate the effects of different routes of administration of carbamazepine during vaginal delivery to prevent postpartum hemorrhage and adverse reactions. Methods A total of 1796 primiparous women with normal vaginal delivery of singleton pregnancies in our hospital from May 2013 to June 2014 were randomly divided into sublingual group, rectal group and vaginal group. After 2 weeks of postpartum hemorrhage The amount of adverse reactions and the occurrence. Results The sublingual group and rectal administration group showed a decrease in the amount of bleeding at 2 h postpartum, which was significantly different from that of the vaginal group (P <0.05). The adverse reaction was the lightest in the vaginal group and high in the rectal group In the sublingual group, prophylactic use of caramel suppository 1 mg was more effective than carbapenem 2 mg in adverse reactions (P <0.05). Conclusion The fetal sublingual carbamazepine suppository 1 mg when delivered, convenient medication, small adverse reactions.