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目的分析经纤维支气管镜注入100%石碳酸溶液治疗支气管胸膜瘘的疗效。方法回顾性分析辽宁省肿瘤医院2009年2月至2012年3月术后并发支气管胸膜瘘患者12例的临床资料,其中男11例,女1例;年龄58.0(45~71)岁;全组患者均为原发性肺癌,其中鳞癌8例,腺癌4例;中心型肺癌8例,周围型肺癌4例;3例行右全肺切除术,6例行左全肺切除术,2例行右肺中下叶切除术,1例行左肺上叶切除术。患者经纤维支气管镜滴注100%石碳酸溶液,每次0.5~1.0 ml滴至支气管胸膜瘘黏膜处,观察胸腔闭式引流管气体溢出情况,若1周后仍有气体溢出可反复注射。分析其疗效。结果 12例患者有8例经5次石碳酸滴注后瘘口闭合,2例经过7次,2例经过2次治疗后瘘口闭合。瘘口平均闭合时间33 d,除2例患者因体弱分别住院42 d和50 d外,其余患者均于门诊治疗痊愈,总有效率100%。结论经纤维支气管镜瘘口内滴注100%石碳酸溶液治疗支气管胸膜瘘疗效确切。
Objective To analyze the curative effect of bronchopleural fistula treated with 100% carbolic acid solution by fiberoptic bronchoscopy. Methods The clinical data of 12 patients with postoperative bronchopleural fistula in Liaoning Cancer Hospital from February 2009 to March 2012 were retrospectively analyzed, including 11 males and 1 females, aged 58.0 (45-71) years old. All the patients Patients were primary lung cancer, including 8 cases of squamous cell carcinoma, 4 cases of adenocarcinoma; 8 cases of central lung cancer, 4 cases of peripheral lung cancer; 3 cases of right pneumonectomy, 6 cases of left pneumonectomy, 2 Routine right lower lobe resection of the lung, 1 case of left upper lobe resection. Patients with bronchoscopy 100% bicarbonate infusion of carbolic acid solution, each 0.5 ~ 1.0 ml drops to the bronchial fistula mucosa at the closure of thoracic drainage tube gas spills, if one week after gas spills are still repeated injection. Analysis of its efficacy. Results Of the 12 patients, 8 had fistula closure after 5 times of carbonic acid drip infusion, 2 after 7, and 2 after 2 treatments. The average closure time of the fistula was 33 days. Except for 2 patients who were hospitalized weakly for 42 and 50 days, all the other patients were recovered in outpatient department and the total effective rate was 100%. Conclusions The treatment of bronchopleural fistula with 100% carbolic acid solution by bronchoscopic fistula is effective.