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目的：研究人的初生时B_(19)感染状况及与母体的感染的相关关系。方法:采用巢式PCR法配对检测101对新生儿-产妇血中B19DNA。结果：①子体（新生儿）与母体（产妇）B19阳性3对（2．97％）、子体与母体均阴性71对（70．30％）、子体阳性母体阴性17对（16．83％），子体阴性母体阳性10对（9．90％）；②101对中103例新生儿（含两对双胞胎）B19检出率19．42％与产妇B19检出率12.87％比较差异无显著性，但显著高于本地区正常人群B19检出率8．72％（P＜0．01）；③20例B19阳性新生儿中2例为先天性脑积水与水肿儿。结论：新生儿及其母体产妇B19感染率较正常人群及著升高，产妇与新生儿B19检出率差异不大，B19母婴垂直传播与致畸作用有待进一步探讨。
Objective: To study the relationship between B 19 infection and maternal infection in human primary. Methods: Nested PCR was used to detect 101 pairs of B19 DNA in neonates and maternal blood. Results: (1) There were 3 pairs (2.97%) of B19 positive in offspring and maternal (maternal), 71 pairs (70.30%) negative in progeny and maternal, 17 negative in positive progeny (16. 83%), and 10 (9.90%) were negative in the progeny negative mother; ② The detection rate of B19 in 103 newborns (including two pairs of twins) in 101 pairs was 19.42% compared with 12.87% in maternal B19 But significantly higher than the normal population in the region B19 detection rate of 8.72% (P <0.01); ③20 cases of B19-positive neonates in 2 cases of congenital hydrocephalus and edema children. Conclusion: The prevalence of B19 infection in newborns and their maternal mothers is higher than that in the normal population. There is no significant difference in the detection rate of B19 among mothers and newborns. The vertical transmission and teratogenic effects of B19 in maternal and infant need to be further explored.