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尽管用于诊断和治疗的血管造影和内窥镜检查有所进展,但由于消化道出血常为间歇性和一过性等原因,而使对急性消化道出血者的处理仍感困难。侵入性诊断技术对活动性出血的定位和治疗价值虽高,但难以把握最佳检查时机,尤其在下消化道出血者,不但无法监测出血情况,而且患者往往年迈多病,使此类检查的危险性增加。早在50年代就对消化道出血采用非侵入性检查,即静脉注射~(51)铬标记红细胞后收集粪便数天,作放射量测定,但此法因太麻烦而未被广泛接受。于70年代,有人用过~(99m)锝酸盐进行腹部闪烁扫描,对诊断Meckel憩室有效。静脉注射的过~(99m)锝酸盐与血浆蛋白疏松结合,并浓聚于甲状腺、唾液腺和胃粘膜内,而40～50%
Despite advances in angiography and endoscopy for diagnosis and treatment, acute gastrointestinal bleeding is still difficult to handle due to intermittent and transient gastrointestinal bleeding. Invaded diagnostic techniques are of high value for the location and treatment of active bleeding, but it is difficult to grasp the optimal timing of the examination, especially in patients with lower gastrointestinal bleeding, not only to monitor bleeding but also to patients who are often elderly and ill, making such tests dangerous Sex increases. As early as 50 years on the gastrointestinal bleeding non-invasive inspection, that is, intravenous injection of ~ (51) chromium labeled red blood cells after collecting feces for several days for the determination of radioactivity, but this method is too cumbersome and not widely accepted. In the 70s, someone used ~ (99m) technetium for scintigraphy of abdomen, which was effective in diagnosing Meckel diverticulum. Intravenous trans- (99m) pertechnetate binds loosely to plasma proteins and accumulates in the thyroid, salivary glands and gastric mucosa, while 40-50%