论文部分内容阅读
目的:探讨肺癌MRI信号强度与DNA倍体的关系。材料与方法:26例肺癌患者,术前用Resonex0.38T磁共振成像系统,行横断面 SE T_1加权,GR序列成像,增强后行 SE T_1加权成像。术后标本用 ICM-100细胞图像分析仪,测定该例肺癌的DNA含量及SPF值。结果:T_1加权平扫二倍体肿瘤信号强度比(病变/椎体)显著小于异倍体肿瘤的信号强度比。二倍体肿瘤的SP值也显著小于异倍体肿瘤的SPF值。但肿癌MRI信号强度比不能反映其SPF值。结论:MRI信号强度在一定程度上可反映肿瘤细胞的倍体情况,即可间接地反映肿瘤细胞的生物学行为。
Objective: To investigate the relationship between MRI signal intensity and DNA ploidy in lung cancer. MATERIALS AND METHODS: Twenty-six patients with lung cancer underwent preoperative resolution of the Resonex 0.38T magnetic resonance imaging system with SE T_1 weighted and GR sequence imaging and enhanced with SE T_1 weighted imaging. Postoperative specimens using ICM-100 cell image analyzer to determine the case of lung cancer DNA content and SPF value. Results: The T 1 weighted mean diploid tumor signal intensity ratio (lesion / vertebral body) was significantly less than the aneuploidy tumor signal intensity ratio. The SP value of diploid tumors was also significantly smaller than that of aneuploid tumors. However, the MRI signal intensity ratio of tumor can not reflect the SPF value. Conclusion: MRI signal intensity can reflect the ploidy status of tumor cells to a certain extent, which can indirectly reflect the biological behavior of tumor cells.