MicroRNA-185-5p mediates regulation of SREBP2expression by hepatitis C virus core protein

• 作 者: Li Min Wang Qi Liu Shun-Ai
• 机 构: PekingUniv,CapitalMedUniv
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2015年15期
• 关键词: CHOLESTEROL HEPATITIS C VIRUS CORE protein miR-185-5p STEATOSIS STEROL response
• 基金项目: Supported by Medical Specialty Development Projects of Beijing Municipal Administration of Hospitals,No.ZYLX201402,Ministry of Education of The People’s Republic of China,No.20121107110012,Beijing Mun

AIM To investigate the molecular mechanism forregulation of cholesterol metabolism by hepatitis Cvirus （HCV） core protein in HepG2 cells.METHODS： HCV genotype 1b core protein was clonedand expressed in HepG2 cells. The cholesterol contentwas determined af