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1982年FAB组提出骨髓增生异常综台征(MDS)的分型建议,促进了国内外对白血病前期(PL)的研究,进展相当迅速。近年来除有大量论文发表之外,还有一些专著出版,对PL(MDS)作了全面系统的阐述,现就其中几个有关问题作简要介绍。命名与发生学 PL是一种造血功能异常的综合征,常常(但不一定)发展为急性髓性白血病(AML),其主要特征是无效应造血、白细胞减少及骨髓增生旺盛,在本世纪初就已受到注意。但PL的概念是到了50年代初,才由Block提出,主要是指急性白血病(AL)
In 1982, the FAB group proposed the classification of myelodysplastic syndrome (MDS) and promoted the research of pre-leukemia (PL) both at home and abroad, which progressed quite rapidly. In addition to a large number of papers published in recent years, there are still some monographs published on the PL (MDS) made a comprehensive and systematic description of several of these issues are briefly introduced. Naming and Epidemiology PL is a syndrome of hematopoietic dysfunction that often (but not necessarily) develops into acute myeloid leukemia (AML) whose main hallmark is unresponsiveness to hematopoiesis, leucopenia and myeloproliferation. At the turn of the century Has been attention. But the concept of PL is to the early 50s, Block proposed, mainly refers to acute leukemia (AL)