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导电聚合物通过其独特的电活性或导电性,可智能地传递或控制细胞电化学信号,从而定向诱导组织器官的再生修复,已成为神经和组织工程领域研究的热点。本文主要介绍了我们实验室生物可降解电活性苯胺聚合物的相关工作,介绍了以苯胺齐聚物与可降解高分子接枝或嵌段制备具有电活性、可生物降解的新型导电聚合物及其在细胞培养和组织工程方面的研究。介绍了静电纺丝制备电活性纳米纤维的概况。苯胺齐聚物与可降解聚合物的接枝和嵌段可同时赋予其电活性、生物相容性和生物可降解性。可生物降解的电活性聚合物是未来生物组织工程领域的发展趋势之一,具有广阔的应用前景。
Conductive polymers, through their unique electrical activity or conductivity, can intelligently transfer or control the electrochemical signals of cells, which can induce the regeneration and repair of tissues and organs organically. It has become a hot research field in nerve and tissue engineering. This paper mainly introduces the related work of biodegradable electroactive aniline polymers in our laboratory, and introduces the preparation of new electrically conductive and biodegradable new conductive polymers with aniline oligomers and biodegradable polymers, Its research in cell culture and tissue engineering. The electrospinning preparation of electroactive nanofibers is introduced. Grafting and blocks of aniline oligomers and degradable polymers can simultaneously impart their electroactivity, biocompatibility and biodegradability. Biodegradable electroactive polymers is one of the future trends in the field of biological tissue engineering, and has broad application prospects.