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血胆固醇增高是冠心病一个风险因素。有研究表明,胆固醇水平低预示着50岁以下冠心病及各种原因的死亡率低。但在30年的随访中,最初14年胆固醇水平低,则后15年死亡风险增高。高密度脂蛋白胆固醇具有独立的保护性作用,也尚未得到大量研究的证实。甘油三酯水平也与心脏疾病有关,并与体重、总脂蛋白胆固醇及低密度脂蛋白胆固醇呈正相关,与高密度脂蛋白胆固醇呈负相关。它是血脂中变化最快的,但不是一种独立的冠心病风险因素,这在分析降脂药物的临床效果时非常承要。心肌梗塞后幸存者的预后,主要受已发生的心肌损伤的程度控制,敝血胆固醇水平并非是主要风险因素。
Increased blood cholesterol is a risk factor for coronary heart disease. Some studies have shown that low cholesterol levels predict coronary heart disease under 50 years of age and various causes of mortality is low. However, at 30 years of follow-up, low cholesterol levels in the first 14 years increase the risk of death after 15 years. High-density lipoprotein cholesterol has an independent protective effect, it has not yet been confirmed by a large number of studies. Triglyceride levels are also associated with heart disease and are positively correlated with body weight, total lipoprotein cholesterol and low density lipoprotein cholesterol, and negatively with high density lipoprotein cholesterol. It is the fastest-changing lipid but is not an independent risk factor for coronary heart disease, which is a burden in analyzing the clinical effects of lipid-lowering drugs. The prognosis of survivors after myocardial infarction is largely controlled by the extent of myocardial damage that has occurred and the level of total cholesterol is not a major risk factor.