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目的:回顾性分析总结影响子宫颈癌预后的高危因素。方法:对2003年1月～2008年12月间中山大学附属第三医院妇科收治的116例子宫颈癌病例进行回顾性分析,进一步探讨病理类型、组织学分级、肌层浸润深度、淋巴结转移、临床分期与预后之间的关系。结果:临床分期(P=0.022)、病理类型(P=0.003)、组织学分级(P=0.000)、盆腔淋巴结转移(P=0.008)与宫颈癌预后显著相关;年龄(P=0.236)、肿瘤直径(≤4 cm vs>4 cm)(P=0.491)、宫颈肌层浸润深度(P=0.270)与预后无显著相关。COX回归多因素分析,临床分期、组织学分级对生存时间的影响差异有统计学意义(P<0.05)。结论:病理类型、组织学低分化、淋巴结转移、期别晚是提示预后不良的高危因素。
Objective: To retrospectively analyze the risk factors of cervical cancer prognosis. Methods: One hundred and sixty-one cases of cervical cancer admitted to the Third Affiliated Hospital of Sun Yat-sen University from January 2003 to December 2008 were retrospectively analyzed. The pathological type, histological grade, depth of myometrial invasion, lymph node metastasis, Staging and prognosis of the relationship. Results: There was a significant correlation between clinical stage (P = 0.022), histological type (P = 0.003), histological grade (P = 0.000) and pelvic lymph node metastasis The diameter (≤4 cm vs> 4 cm) (P = 0.491), cervical myometrial invasion depth (P = 0.270) had no significant correlation with prognosis. COX regression multivariate analysis, clinical stage, histological grade on the survival time difference was statistically significant (P <0.05). Conclusion: The pathological type, histological poor differentiation, lymph node metastasis, late-stage prognosis is a risk factor for poor prognosis.