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本文报告阿米巴病患者使用皮质类固醇(以下简称激素)不仅可诱发且加重阿米巴肠病,又可使阿米巴肝病患者发生暴发性的进展。例1为26岁男性。因右肩痛服用强的松20mg/日,10天后发生严重的血性腹泻和消瘦伴右肩疼痛加重。体检除右上腹压痛外无特殊发现。粪便检得溶组织内阿米巴。肝扫描示右叶大块缺损,乃确诊为阿米巴肝脓肿,肝穿刺抽出棕色脓液200ml,经依米丁和灭滴灵等药物治疗后痊愈。例2为43岁男性。因疲劳、胃纳减退和右上腹痛入院。体检无特殊发现,肝功能和粪便检查均无特殊发现。肝活检呈慢性活动性肝炎(以下简称慢活肝),患者病程中曾有2次发热,其后的10周内患者体温正常,仅血清丙种球蛋白升高(从1.1增至2.4g%),乃开始激素治疗60mg/日,
This article reports the use of corticosteroids in patients with amebiasis (hereinafter referred to as hormones) not only induce and aggravate enteric bowel disease, but also make the occurrence of fulminant disease in patients with amoebolic progression. Example 1 is a 26 year old male. Due to the right shoulder pain prednisone 20mg / day, 10 days after severe bloody diarrhea and emaciation with right shoulder pain increased. Physical examination except for the right upper quadrant tenderness no special findings. Fecal sequestration of Entamoeba histolytica. Hepatic scan showed right lobe large defect, is diagnosed as amoebic liver abscess, liver puncture pulls out brown pus 200ml, according to Meidin and metronidazole and other drugs cured. Example 2 is a 43-year-old man. Due to fatigue, decreased appetite and right upper quadrant pain hospitalization. No special physical examination, liver function and stool examination were no special findings. Liver biopsy was chronic active hepatitis (hereinafter referred to as slow living liver), the patient had two fever in the course of the course of the next 10 weeks in patients with normal temperature, serum gamma globulin only increased (from 1.1 to 2.4g%) , Is the beginning of hormone therapy 60mg / day,