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目的:寻找慢性每日头痛的有效治疗方法。方法:选择符合慢性每日头痛的变形性偏头痛和慢性紧张型头痛诊断标准的216例患者,给予舍曲林50～100mg治疗,共8周,于治疗前、治疗4周及8周后根据患者头痛的严重程度和汉密尔顿抑郁量表进行量化评定各一次,共3次。结果:总有效率为59.7%,CTTH患者有效率57%,显效51例(30%),有效45例(27%);TM患者有效率为68%,显效27例(55%),有效6例(13%)。结论:舍曲林治疗慢性头痛不良反应少且易耐受,疗效与是否合并抑郁无关。
Objective: To find an effective treatment for chronic daily headache. METHODS: A total of 216 patients with metformin and chronic tension-type headache who met the criteria of chronic daily headache were given sertraline 50-100 mg for 8 weeks before treatment, 4 weeks and 8 weeks after treatment The severity of headache and the Hamilton Depression Scale were quantified one time for three times. Results: The total effective rate was 59.7%, effective rate was 57% in CTTH patients, effective rate was 51 (30%) and effective rate was 45 (27%). The effective rate of TM was 68%, effective rate was 27 (55%), effective 6 Example (13%). Conclusion: Sertraline has few side effects and is easy to tolerate chronic headache.