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本文报告了从9Kg猪骨中提取和纯化出猪骨形态发生蛋白(pBMP)6.8mg,并证明该蛋白能在小鼠肌内和皮下诱导新骨的产生,电镜观察和碱性磷酸酶染色提示植入区域有较多的成骨细胞出现,并有活跃的蛋白合成和分
This paper reports the extraction and purification of 6.8 mg of pBMP from 9 kg pork bone and demonstrates that the protein induces the production of new bone both in the muscle and in the skin of the mice by electron microscopy and alkaline phosphatase staining There are more osteoblasts in the implanted region and active protein synthesis and fractionation