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对991个健康、中等阶层、成年(30—59岁)的白种男人中的95人的家族进行了研究。他们的空腹血浆脂类水平等于或高于对照分布的95％分位数。这些家族是按我们组以前在心肌梗塞幸存者的家族研究中使用过的体系来分类的(Goldstein,J.L.et al1973.J.Clin.Invest.52,1533—1577)。 76个家族中至少包括3个可利用的一级亲属,并可进一步分级。与家族性高胆固醇血症一致的样本有2家(0.2％),与家族性高甘油三酯血症一致的样本有8家(0.8％)
A study of 95 families of 991 healthy, middle-class, adult (30-59 years) white men was conducted. Their fasting plasma lipid levels were equal to or above the 95% quantiles of the control distribution. These families are classified according to the previous systems used by our group in familial studies of myocardial infarction survivors (Goldstein, J.L. et al1973. J. Clin. Invest. 52, 1533-1577). The 76 families include at least three available first-degree relatives and can be further graded. Two families (0.2%) matched familial hypercholesterolemia and eight (0.8%) matched familial hypertriglyceridemia