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目的:探索药师在临床抗菌药物合理应用中的作用,促进临床合理用药。方法:选取医院外科2015年6月~2016年6月住院患者为研究对象,药师进行干预。根据科室实际情况开展抗菌药物管理工作,制定合理的管理制度,指导临床合理用药,加强医护人员培训,并加强监督和反馈。比较药师干预前后抗菌药物使用情况、抗菌药物使用不合理率及病原学送检率等。结果:通过药师的干预,干预组抗菌药物使用种类、用药天数及住院时间均较干预前有了显著下降(P<0.05)。干预组选药不合理、联合用药不合理、剂量不合理、用药时机不合理均有了显著下降(P<0.05)。病原学送检率较干预前有了显著上升(P<0.05)。结论:加强药师的服务功能,有助于提高临床抗菌药物的合理应用。
Objective: To explore the role of pharmacists in the rational application of clinical antimicrobial agents to promote clinical rational use of drugs. Methods: Inpatients from hospital surgery from June 2015 to June 2016 were selected as research subjects and pharmacists to intervene. According to the actual situation of departments to carry out antimicrobial drug management, develop a reasonable management system, to guide clinical rational use of drugs, strengthen training of health care workers, and strengthen supervision and feedback. Before and after the intervention pharmacist compared antimicrobial use, the use of anti-bacterial drugs and unreasonable rate of etiology. Results: Through the intervention of pharmacists, the types of antimicrobial agents used, the days of treatment and length of stay in the intervention group were significantly lower than those before intervention (P <0.05). In the intervention group, the drug selection was unreasonable, the combination therapy was unreasonable, the dose was irrational, and the irrational timing of medication was significantly reduced (P <0.05). The rate of etiological examination was significantly higher than that before intervention (P <0.05). Conclusion: To strengthen the service function of pharmacists helps to improve the rational application of clinical antimicrobial agents.