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调查５８名镉（Ｃｄ）作业工人尿中γ－ＧＴ同功酶的变化。结果发现，所有Ｃｄ作业工人尿中γ－ＧＴ，γ－ＧＴⅠ，γ－ＧＴⅡ均超出正常值上限。无肾损伤组的工人尿γ－ＧＴ，７·ＧＴⅠ，γ－ＧＴⅡ明显地高于对照组，而γ－ＧＴⅠ／γ－ＧＴⅡ值无明显变化；重度肾损伤组，尿γ－ＧＴ，γ－ＧＴⅠ水平高于无肾损伤和进度肾损伤组，而尿γ－ＧＴⅠ／γ－ＧＴⅡ则呈下降趋势。结果提示，尿γ－ＧＴ可能作为Ｃｄ接触者健康监测的一个敏感指标；尿γ－ＧＴⅠ／γ－ＧＴⅡ值的变化似与Ｃｄ作业工人肾损伤程度有关。
Urine γ-GT isoenzymes in 58 cadmium workers were investigated. The results showed that γ-GT, γ-GTⅠ, γ-GTⅡ in urine of all Cd workers exceeded the upper limit of normal value. The urinary γ-GT, 7 · GTⅠ and γ-GTⅡ in the group without renal injury were significantly higher than those in the control group, but there was no significant change in γ-GTⅠ / γ- The level of GTⅠwas higher than that of the group without renal injury and progression of renal injury, while the urinary γ-GTⅠ / γ-GTⅡwere decreased. The results suggest that urinary γ-GT may be used as a sensitive indicator of health monitoring in Cd-exposed patients. The change of urinary γ-GTⅠ / γ-GTⅡmight be related to the degree of renal injury in Cd-exposed workers.