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背景:不孕不育是一种重大的生活危机,它可以导致精神病症状的发展并且对夫妻的生活质量产生负面影响,但其影响程度可能取决于文化背景。目标:我们比较了土耳其城市中生育妇女和不孕妇女的精神病症状程度、功能障碍水平和生活质量。方法:该横断面研究纳入了100名在里泽教育和研究医院的妇产科门诊治疗不孕不育的已婚女性和100名已婚已育的妇女作为对照组。对所有参与者均采用社会人口信息筛查表、医院焦虑抑郁量表(Hospital Anxiety and Depression Scale,HADS)、简单功能障碍问卷(Brief Disability Questionnaire,BDQ)和健康状况问卷(Short Form Health Survey,SF-36)进行评估。结果:不育女性的平均焦虑分量表得分和抑郁分量表得分稍高于对照组,但差异无统计学意义。不孕组妇女中有显著临床焦虑症状的比例(即焦虑分量表得分>11)显著高于育龄妇女(31%v.17%,X~2=5.37,p=0.020),但有显著临床抑郁症状的比例(即抑郁分量表评分HADS>8)在两组间没有显著性差异(43%v.33%,X~2=2.12,p=0.145)。不育女性自我报告前一个月的功能障碍显著比对照组严重,并且不育女性在SF-36的8个分量表中4个(一般健康、活力、社会功能和心理健康)显著差于对照组。与目前工作的不育女性相比,目前没有工作的女性不育患者报告的抑郁和焦虑程度较轻,且一般健康状况、活力和心理健康状况较好。结论:未发现土耳其城市地区中寻求治疗的不孕不育已婚女性并比已婚已育妇女有更严重的抑郁症状,但他们确实报告有较大的躯体和心理障碍并且生活质量较差。不孕不育的负面影响对在职不孕女性妇女比无业的不孕妇女更严重。西方国家这通常报告不孕患者抑郁和焦虑的患病率更高,我们需要更大规模的随访研究以评估这些结果与西方国家报告的结果不同的原因。
Background. Infertility is a major life crisis that can lead to the development of psychotic symptoms and negatively affect the quality of life of couples, but the extent of their impact may depend on the cultural context. Objectives: We compared psychiatric symptoms, dysfunction levels and quality of life among childbearing and infertile women in Turkish cities. METHODS: This cross-sectional study enrolled 100 obstetric and gynecological outpatient clinics at the Rize Education and Research Hospital to treat infertile married women and 100 married and fertile women as controls. All participants used social demography information screening, Hospital Anxiety and Depression Scale (HADS), Brief Disability Questionnaire (BDQ) and Short Form Health Survey (SF) -36). Results: The average score of anxiety subscale and depression subscale of infertile women were slightly higher than that of the control group, but the difference was not statistically significant. The proportion of women with infertility who had significant clinical anxiety symptoms (ie, anxiety subscale score> 11) was significantly higher in women of reproductive age (31% v.17%, X 2 = 5.37, p = 0.020) There was no significant difference (43% v.33%, X ~ 2 = 2.12, p = 0.145) in the proportion of symptoms (ie, depression subscale score HADS> 8) between the two groups. The dysfunction of infertile women one month prior to self-report was significantly worse than that of the control group, and four infertile women (general health, vitality, social functioning and mental health) were significantly worse than the control group in the 8 subscales of SF-36 . Female infertility patients who currently do not work report lower levels of depression and anxiety than normal working women and generally show better health, vitality and mental health. CONCLUSIONS: Infertile married women seeking treatment in Turkey’s urban areas were found to have more severe depressive symptoms than married and fertile women, but they did report large physical and psychological disabilities and poor quality of life. The negative effects of infertility are more serious for working female infertile women than for unemployed infertile women. Western countries This generally reports a higher prevalence of depression and anxiety in infertile patients and we need a larger follow-up study to assess the reasons for these differences in results from those reported in Western countries.