论文部分内容阅读
目的探讨放射介入疗法经胃动脉药物灌注化疗、栓塞治疗原发性胃癌疗效。方法对23例失去手术机会原发性胃癌患者采用经胃动脉药物灌注化疗及栓塞治疗;对胃底贲门部的中晚期原发性胃癌患者,再加碘液和明胶海绵碎屑栓塞。各例行3次介入治疗后,观察疗效并随访。结果23例患者中,82.6%(19/23)患者临床自觉症状减轻或消失,其总有效率(显效+有效)为78.3%(18/23)。随访12、24、36月的生存率分别是52.2%(12/23)、30.4%(7/23)、8.7%(2/23)。结论经胃动脉药物灌注化疗、栓塞治疗中晚期原发性胃癌有较满意的近期疗效,癌灶缩小,患者临床自觉症状减轻或消失,生存期得以延长,其对已失去手术机会的原发性胃癌患者具有一定的治疗价值。
Objective To investigate the efficacy of radiation interventional therapy through gastric arterial infusion chemotherapy and embolization in the treatment of primary gastric cancer. Methods Twenty-three patients with primary gastric cancer who had lost the operation chance were treated with chemotherapy and embolization of transcatheter arterial chemoembolization. The patients with advanced gastric cancer with cardia and stomach were treated with iodine and gelatin sponge embolization. After 3 routine interventions, the curative effect and follow-up were observed. Results Of the 23 patients, 82.6% (19/23) of patients with clinical symptoms relieved or disappeared, the total effective rate (effective + effective) was 78.3% (18/23). Survival rates at 12, 24 and 36 months after follow-up were 52.2% (12/23), 30.4% (7/23) and 8.7% (2/23), respectively. Conclusion Gastrointestinal arterial infusion chemotherapy, embolization in the treatment of advanced primary gastric cancer have more satisfactory short-term curative effect, reduce the size of the lesion, patients with clinical symptoms relieved or disappeared, the survival period can be extended, its has lost the opportunity of primary surgery Gastric cancer patients have a certain therapeutic value.