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目的探讨动态血清孕酮(P)及β-人绒毛膜促性腺激素(β-HCG)水平对早期异常妊娠的临床意义。方法选择湖南省妇幼保健院妇科收治的孕龄6~8周伴有阴道出血的患者114例,按妊娠结局分先兆流产继续妊娠组(62例)、难免流产组(18例)、输卵管妊娠组(34例),动态监测血清P及β-HCG水平,对资料进行统计学分析。结果先兆流产继续妊娠组动态血清P及β-HCG水平均显著高于其它两组(P<0.05);先兆流产继续妊娠组动态血清β-HCG水平呈上升趋势,难免流产组动态血清P及β-HCG水平呈下降趋势;输卵管妊娠组动态血清P及β-HCG水平均显著低于其它两组,差异有统计学意义(P<0.05)。结论动态监测血清P及β-HCG水平对早期异常妊娠的诊断和治疗有非常重要的临床意义,值得临床推广和普及。
Objective To investigate the clinical significance of serum progesterone (P) and β-human chorionic gonadotropin (β-HCG) levels in early abnormal pregnancy. Methods 114 patients with gestational age of 6-8 weeks with vaginal bleeding admitted to gynecology hospital of MCH in Hunan Province were enrolled in this study. According to the outcome of pregnancy, threatened abortion continued pregnancy group (62 cases), inevitable abortion group (18 cases), tubal pregnancy group (34 cases). The levels of serum P and β-HCG were monitored dynamically, and the data were statistically analyzed. Results The levels of serum P and β-HCG in the patients with threatened abortion continued to be significantly higher than those in the other two groups (P <0.05). The level of serum β-HCG in the pregnant women with threatened abortion continued to increase, and the dynamic serum P and β -HCG levels showed a downward trend; tubal pregnancy group serum P and β-HCG levels were significantly lower than the other two groups, the difference was statistically significant (P <0.05). Conclusions The dynamic monitoring of serum P and β-HCG levels has very important clinical significance for the diagnosis and treatment of early abnormal pregnancy, which is worthy of clinical promotion and popularization.