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蛛网膜下腔出血所致血管痉挛的病人发生神经功能缺失,其最大的可能是由于继发性脑血流减少.本文作者报告对10例血管痉挛伴有症状患者以大剂量白蛋白制剂进行治疗.10例均为颅内动脉瘤破裂蛛网膜下血出血,经血管造影证实因脑血管痉挛而出现神经功能障碍.其中9例为前交通动脉动脉瘤,1例为大脑中动脉动脉瘤.入院时临床分级(按Hunt和Kosnik)为1～4级.4例于手术夹闭动脉瘤并清除蛛网膜下腔血凝块后发生血管痉挛,4例于血管痉挛所致神经功能障碍恢复后方行延期手术,另2例拒绝手术.所有病例均在一经出现神经功能障碍即给予大剂量的白蛋白治疗.注入白蛋白的剂量为0.7～2克/公斤/天,
Patients with vasospasm due to subarachnoid hemorrhage may have neurological deficits, the greatest of which may be due to secondary cerebral blood flow reduction. The authors report the treatment of 10 patients with symptomatic vasospasm with high-dose albumin .10 cases were intracranial aneurysm rupture subarachnoid hemorrhage, angiography confirmed by cerebral vasospasm and neurological dysfunction.Among them, 9 cases of anterior communicating artery aneurysm, and 1 case of middle cerebral artery aneurysm.Admission The clinical grade (by Hunt and Kosnik) was grade 1 to 4. In 4 cases, vasospasm occurred after the aneurysm was closed and the subarachnoid space was cleared, and 4 cases were recovered after nerve dysfunction caused by vasospasm Delayed surgery, and the other two refused surgery.All patients were given large doses of albumin in the event of neurological dysfunction.The dose of albumin injection was 0.7-2 g / kg / day,