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目的 研究嗜麦芽窄食单胞菌引起的感染危险因素及有效抗生素。方法 分析12例嗜麦芽窄食单胞菌感染的临床资料，应用Sceptor系统测定了18株嗜麦芽窄食单胞菌对20种抗性素的敏感度。结果 嗜麦芽窄食单胞菌多见于呼吸道感染，其次为菌血症及局部感染。分离菌株对大多数抗生素耐药。结论 严重基础疾病、临床应用广谱抗生素及免疫抑制剂是嗜麦芽窄食单胞菌感染的危险因子。替卡西林、环丙沙星和阿米卡星为抗嗜麦芽窄食单胞菌有相对活性的抗生素。“,”Objective To control the infections caused by Stenotrophomonas maltophilia.Methods To analyse the clinical data of 12 patients,from whom Stenotrophomonas maltophilia hadbeen isolated. The susceptibility of 18 strains of Stenotrophomonas maltophilia to 20 antibiotics weremeasured by Sceptor system. Results Infection of respiratory tract, bacteriemia and local infectionwere most common. The isolated strains of Stenotrophomonas maltophilia were resistent to most ofantibiotics. Conclusion Severe base disease,clinical application of broad-spectrumed antibiotics orimmunosuppressants may be the risky factors for infections caused by Stenotrophomonas maltophilia.Ticarcillin, Ciprofloxacin and Amikacin are the relatively active antibiotics against Stenotrophomonasmaltophilia.