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作者报告了122例特发性骨髓纤维化患者的治疗,患者年龄31～71岁,男性54例,女性68例,病程几个月～27年,2/3有骨组织肿瘤。作者根据患者疾病经过的个体特点进行用药。在早期无显著贫血而脾脏中度肿大(13例)时,仅予以全身强壮疗法。在因生血不足而有中度贫血时,用雄激素治疗(5例单用,105例与其他药物并用)。雄激素可促进血红蛋白的增高,显著减少患者输血的需要。肾上腺皮质激素治疗(30例)用于有溶血性贫血、脾功能亢进、生血不足、长期发热及关节
The authors reported 122 patients with idiopathic myelofibrosis who were 31-71 years old, 54 males and 68 females, with a course of several months to 27 years and two thirds had bone tumor. According to the patient’s disease through the individual characteristics of medication. In the early no significant anemia and moderate enlargement of the spleen (13 cases), only the body to be strong therapy. In moderate anemia due to lack of blood when androgen therapy (5 cases of single use, 105 cases with other drugs). Androgen can promote increased hemoglobin, significantly reducing the need for blood transfusions in patients. Corticosteroid therapy (30 cases) for hemolytic anemia, hypersplenism, hypoxemia, long-term fever and joints