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  5. Hypersensitive Inhibition of the Proliferation of Cells with Mutated DNA Repair-Related Genes by the

Hypersensitive Inhibition of the Proliferation of Cells with Mutated DNA Repair-Related Genes by the

来源 :药理与制药(英文) | 被引量 : 0次 | 上传用户：zhou1022
【摘 要】
：
We previously reported that many ingenol compounds derived from Euphoria kansui exhibit topoisomerase inhibitory activity. 20-O-ingenolEZ in these compounds exe
【作 者】
：
Masahiro Kanbe Yasuaki Fukuda 
【机 构】
：
DepartmentofChemistry,SchoolofPharmacy,SchoolofPharmacy
【出 处】
：
药理与制药(英文)
【发表日期】
：
2012年2期
【关键词】
：
CATALYTIC TOPO II INHIBITOR DNA Damage CHECKPOINT DNA Repair-Related Genes Ingen 
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We previously reported that many ingenol compounds derived from Euphoria kansui exhibit topoisomerase inhibitory activity. 20-O-ingenolEZ in these compounds exerted inhibitory effects on both topoisomerase II (topo II) activity and cell proliferative acti
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