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目的:对纳洛酮治疗小儿急性中枢性呼吸衰竭的临床疗效进行探讨。方法:随机抽取我院在2011年1月-2013年12月治疗的82例小儿急性中枢性呼吸衰竭,分为两组:观察组与对照组,对照组患儿使用基础方案进行治疗,而观察组患儿在基础方案的基础上再使用纳洛酮,对两组患儿的治疗效果进行对比与分析。结果:观察组患儿的治疗总有效率明显高于对照组,存在较大差异,具备统计学意义(P<0.05)。观察组患儿的血气、症状改善情况明显优于对照组,存在较大差异,具备统计学意义(P<0.05)。结论:纳洛酮在小儿急性中枢性呼吸衰竭治疗中的应用,不仅提高了患儿的治疗有效率,而且降低了患儿并发症的发生率,减少了不良反应的出现,具有非常重要的意义,值得在临床治疗中进行大范围的推广与应用。
Objective: To investigate the clinical efficacy of naloxone in the treatment of pediatric acute central respiratory failure. Methods: A total of 82 children with acute central respiratory failure treated in our hospital from January 2011 to December 2013 were randomly divided into two groups: the observation group and the control group, and the control group were treated with the basic protocol, while the observation Group children in the basic program based on the use of naloxone, the treatment of children in two groups were compared and analyzed. Results: The total effective rate of treatment group was significantly higher than that of control group, with significant difference (P <0.05). Observation group of children with blood gas, symptoms improved significantly better than the control group, there is a big difference, with statistical significance (P <0.05). Conclusion: The application of naloxone in children with acute central respiratory failure not only improves the treatment efficiency in children, but also reduces the incidence of complications and reduces the occurrence of adverse reactions, which is of great significance , It is worth in the clinical treatment of a wide range of promotion and application.