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为确定低剂量皮内接种血源性乙型肝炎疫苗后抗体的持久性和对加强剂量的应答,作者对用2μg剂量免疫的两个年级的医学生进行了研究。免疫对象及方案:共有110名89级学生,于三角肌区皮内接种2μg乙型肝炎疫苗,其中97人于0、30和180天接种。97人中有9人前两针由同学间互相注射,88人由2名有经验的护士接种;另13人仅于0和30天接种。20个月时抗-HBs浓度低于10mIU/ml的学
To determine the persistence of antibodies and their response to booster doses following low-dose intradermic Hepatitis B vaccination, the authors studied two grades of medical students who were immunized with 2 μg. Immune Target and Program: A total of 110 students at level 89 received 2 μg of Hepatitis B vaccine intradermally in the deltoid area, 97 of whom were vaccinated on days 0, 30 and 180. Nine out of 97 people were injected with each other by classmates for the first two shots, 88 were vaccinated by two experienced nurses and the other 13 were vaccinated on days 0 and 30. Anti-HBs concentrations below 10 mIU / ml at 20 months