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目的探讨O型血孕妇产前免疫球蛋白G(Ig G)抗体效价检测的异常情况与新生儿溶血病发病之间的关系。方法用微柱凝胶法对1357例O型血孕妇产前血清Ig G抗A(B)抗体进行检测。结果 1357例O型血孕妇血清抗体效价≥1:128者147例,异常检出率为10.8%。结论孕妇产前Ig G抗A(B)效价的检测在预防或减少新生儿溶血病方面有重要意义。
Objective To investigate the relationship between the abnormality of IgM antibody titer in O-type pregnant women and the incidence of hemolytic disease of newborn. Methods Prenatal serum Ig G anti-A (B) antibody was detected by microcolumn gel method in 1357 O-pregnant women. Results Serum antibody titers of 1 577 O type pregnant women were 147 cases with the titer of 1: 128 and the rate of abnormality was 10.8%. Conclusion The detection of prenatal Ig G anti-A (B) titer in pregnant women is of great significance in preventing or reducing neonatal hemolytic disease.