HLA-G在肿瘤中的表达(文献综述)

• 作 者: 王一力
• 机 构: 苏州大学,连云港市第一人民医院,
• 出 处: 放射免疫学杂志
• 发表日期: 2012年03期
• 关键词: HLA-G 细胞表面 肿瘤组织 异构体 黑色素瘤细胞系 乳腺癌 恶性腹腔积液 肿瘤抗原 活检组织

自1987年Geraghty等[1]同事第一次报道发现HLA-G以来,至今已有十余年,人们对这个非经典HLA-I类分子的了解逐渐深入。HLA-G(human leucocyte antigen-G)即人类白细胞抗原系统-G是一种非经典的HLA-I类抗原,它定位于6号染色体短臂HLA远端300bp以内,并选择性的在

Since 1987, when Geraghty et al. [1] reported for the first time that HLA-G was found, it has been more than ten years since then. People have gradually deepened their understanding of this non-classical HLA-I molecule. HLA-G (human leucocyte antigen-G), the human leucocyte antigen-G, is a non-classical HLA-I antigen that is located within 300 bp of the HLA distal end of chromosome 6 and is selectively