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选用16—18克体重的雄性昆明种小鼠,分实验组和对照组,实验组气管内注入宣威烟尘提取物的吐温—80溶液,对照组气管内注入吐温—80溶液,每10日注入一次,共注入10次。结果指出,实验组肺部肿瘤发生率为52.8%,其中肺癌占40.3%,绝大部分为腺癌,对照组肺部肿瘤发生率为25.6%,肺癌占16.3%。两组肺肿瘤发生率之问有显著性差异。另外,实验组肺肿瘤发生时间明显早于对照组。除肺肿瘤外,未发现其它组织的肿瘤发生,证明宣威燃煤烟尘具有明显诱发肺癌的能力。
Sixteen male Kunming mice weighing 16-18 g were divided into experimental group and control group. Tween-80 solution of Xuanwei soot extract was injected intratracheal intratracheal in experimental group, On a daily injection, injected a total of 10 times. The results showed that the incidence of lung cancer in the experimental group was 52.8%, of which 40.3% of lung cancer, the vast majority of adenocarcinoma, lung cancer control group was 25.6%, lung cancer accounted for 16.3%. There was a significant difference between the two groups in the incidence of lung cancer. In addition, the incidence of lung cancer in the experimental group was significantly earlier than that in the control group. In addition to lung tumors, no other tissue tumors were found, demonstrating that Xuanwei coal-fired dust has a clear ability to induce lung cancer.