Tyrosine hydroxylase and Lewy body molecules immunoreactivity in the SNC neurons of an AS/AGU mutant

• 作 者: A. G. Al-Kushi D. Russell A. P
• 机 构: CollegeofMedicine,SchoolofLifeSciences
• 出 处: 神经科学国际期刊(英文)
• 发表日期: 2012年3期
• 关键词: PKC-Gamma TYROSINE HYDROXYLASE UBIQUITIN PARKIN PKC-Gamma Tyrosine Hydroxylase U

The AS/AGU rat has a recessive single point mutation in the gene coding for the gamma isoform of protein kinase C (PKC-γ) resulting in a failure to release dopamine in the striatum and impaired movement including a staggering gait, difficulty in initiatin