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作者分离出高纯度的人外周血T 细胞,探讨IL-6对T 细胞增殖的作用。PHA 和IL-6共同刺激,可诱导T 细胞明显增殖,3HTdR 掺入量比单纯PHA 刺激高3—7倍。但比IL-2加PHA 或放射线照射的单核细胞加PHA 刺激所致T 细胞的3HTdR掺入值低3倍。T 细胞增殖与IL-6/PHA 呈
The authors isolated high purity human peripheral blood T cells to explore the role of IL-6 on T cell proliferation. PHA and IL-6 co-stimulation, can induce significant proliferation of T cells, 3HTdR incorporation 3-7 times higher than simple PHA stimulation. But was 3-fold lower than the 3H-TdR incorporation of T cells by PHA-stimulated monocytes plus IL-2 plus PHA or radiation. T cell proliferation and IL-6 / PHA were