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目的 评价血清肌钙蛋白T(TnT)和C反应蛋白 (CRP)在急性心肌梗死 (AMI)和不稳定型心绞痛 (UAP)的早期诊断及预后评价 .方法 分析了AMI 4 8例 ,UAP 4 5例及健康对照 36人血清CRP、TnT、肌酸激酶 (CK)和同工酶(CK -MB)水平 ,并对结果行配对 χ2 检验 .结果 AMI组入院时血清CRP和TnT阳性率分别为 81.3%和 97.9% ,均明显高于同时间CK和CK -MB的阳性率 (p均 <0 .0 1) ;UAP组血清CRP、TnT、CK及CK -MB阳性率分别为 4 2 .2 %、13.3%、11.1%及 6 .7% .健康对照组 36例四项指标均无 1例阳性 .结论 TnT和CRP在早期辅助诊断AMI和评估UAP患者预后中有应用价值 ,CK、CK -MB和CRP、TnT联合测定可以提高对AMI诊断的准确性
Objective To evaluate the early diagnosis and prognosis of acute myocardial infarction (AMI) and unstable angina pectoris (UAP) in patients with acute myocardial infarction (AMI) and C reactive protein (CRP) The serum levels of CRP, TnT, creatine kinase (CK) and isoenzyme (CK-MB) were detected in 36 healthy volunteers, and the results were paired withχ2 test.Results The positive rates of CRP and TnT in AMI were 81.3 % And 97.9%, respectively, were significantly higher than those of CK and CK-MB at the same time (all P <0.01). The positive rates of serum CRP, TnT, CK and CK-MB in UAP group were 42.2% , 13.3%, 11.1%, and 6.7%, respectively.No positive result was found in 36 cases of healthy control group.ConclusionTnT and CRP have the value of early diagnosis of AMI and prognosis of UAP.CK, CK-MB And CRP, TnT combined determination can improve the accuracy of the diagnosis of AMI