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目的探讨彩色多普勒结合二维超声对胎儿心血管畸形的临床诊断价值,并分析其高危因素。方法采用彩色多普勒超声结合二维及三维超声对2016年3月至2016年9月共1301例在我院就诊孕妇的胎儿进行心脏检查,并对筛查的高危因素进行分析。结果在1301例胎儿中,筛查出18例先天性心脏病,其中,室间隔缺损8例,大动脉转位1例,法洛四联症2例,卵圆孔直径增大(大于6mm)3例,左心发育不良综合征2例,完全性心内膜塾缺损2例。妊娠期合并症、既往异常妊娠史、孕期使用抗生素是胎儿先天性心脏病的危险因素(P<0.05),而年龄、产次不是先天性心脏病的危险因素(P>0.05)。结论彩色多普勒结合二维超声对胎儿先天性心脏病进行筛查是一种灵敏度比较高的检查方法,无创伤性,经济又简便易行,是临床上筛查胎儿先天性心脏病的首选方法之一。
Objective To investigate the value of color Doppler combined with two-dimensional ultrasound in the diagnosis of fetal cardiovascular malformations and to analyze the risk factors. Methods A total of 1301 fetuses from our hospital from March 2016 to September 2016 were examined with color Doppler ultrasound combined with two-dimensional and three-dimensional ultrasonography. The risk factors of screening were analyzed. Results Among 1301 fetuses, 18 cases of congenital heart disease were screened out, including 8 cases of ventricular septal defect, 1 case of transposition of the great arteries, 2 cases of tetralogy of Fallot and the diameter of foramen ovale increased more than 6 mm3 Cases, left heart dysplasia syndrome in 2 cases, complete endocardial private supplementary defect in 2 cases. Pregnancy complications, past history of abnormal pregnancy, antibiotics during pregnancy is a risk factor for fetal congenital heart disease (P <0.05), while age, parity is not a risk factor for congenital heart disease (P> 0.05). Conclusion Color Doppler combined with two-dimensional ultrasound screening for fetal congenital heart disease is a relatively high sensitivity test method, non-invasive, economical and simple and easy, is the screening of fetal congenital heart disease, the first choice for screening One of the ways.