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为探讨慢性乙型肝炎合并巨细胞病毒（ＣＭＶ）感染对肝功能、ＨＢＶ复制的影响，对９３例慢性乙肝分别检测了抗－ＣＭＶＩｇＭ、ＨＢＶＤＮＡ及生化指标；另２０例健康人检测抗－ＣＭＶＩｇＭ作对照。结果显示，慢性乙肝病例中抗－ＣＭＶＩｇＭ阳性率为１８．３％，阳性病例的生化指标ＧＧＴ、ＴＢｉｌｉ高于阴性者，尤其在慢性重度肝炎和肝炎肝硬变病例中（Ｐ＜０．０５）。且阳性病例中ＨＢＶＤＮＡ阳性率亦高于阴性者（Ｐ＞０．０５）。结果提示，ＣＭＶ感染好发于免疫虚损的宿主，又可抑制宿主免疫功能，有利于ＨＢＶ复制，合并ＣＭＶ感染可加重肝功能障碍
To investigate the effect of CMV infection on liver function and HBV replication in chronic hepatitis B patients, anti-CMVIgM, HBVDNA and biochemical markers were detected in 93 chronic hepatitis B patients and 20 healthy individuals were tested for anti-CMVIgM Control. The results showed that the positive rate of anti-CMVIgM in chronic hepatitis B cases was 18.3%, and the biochemical indicators GGT and TBili in positive cases were higher than those in negative ones, especially in patients with chronic severe hepatitis and cirrhosis (P <0.05) . The positive rate of HBVDNA in positive cases was also higher than that in negative ones (P> 0.05). The results suggest that CMV infection occurs in the immune deficiency of the host, but also inhibit the immune function of the host, is conducive to HBV replication, CMV infection may aggravate liver dysfunction