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目的:评价伽马刀放射外科治疗听神经瘤的效果。方法:使用伽马刀对38例听神经瘤患者进行放射外科治疗,放射剂量为14~15Gy,根据住院天数、定期临床体检及核磁共振成像(MRI)扫描结果等,观察肿瘤控制率(肿瘤缩小或无改变),听力及其他颅神经功能保持率,评价治疗效果。结果:31例(81.5%)患者无不适反应,第一天出院,余患者出现轻—中度不适,经观察、对症处理后缓解,均在第二或第三天出院;术后听力保持率为59.3%,1,2,3年肿瘤控制率分别为92.1%、89.5%和87.9%。结论:伽马刀放射外科疗法是听神经瘤安全、有效的治疗方法,值得推广使用。
Objective: To evaluate the effect of gamma knife radiosurgery on acoustic neuroma. Methods: Thirty-eight patients with acoustic neuroma were treated by radiosurgery at a dose of 14 ~ 15Gy using gamma knife. The tumor control rate (tumor reduction or tumor size) was observed according to hospitalization days, regular clinical examination and MRI findings. No change), hearing and other cranial nerve function retention rate, evaluation of the treatment effect. Results: 31 patients (81.5%) had no discomfort reaction. The patients were discharged on the first day, and mild to moderate discomfort was observed in the patients. The patients were relieved after symptomatic treatment and were discharged on the second or third day. The hearing retention rate Was 59.3%. The tumor control rates at 1, 2 and 3 years were 92.1%, 89.5% and 87.9% respectively. Conclusion: Gamma knife radiosurgery is a safe and effective treatment for acoustic neuroma, which is worth promoting.