论文部分内容阅读
亚甲蓝是一种化学性质活泼的氧化还原剂。从前多用于治疗和抢救高铁血红蛋白血症,在外科临床的应用颇为有限,近年来进行了较为广泛的研究,并取得了可喜的进展,现在介绍如下。 1 亚甲蓝染色用于胰岛素瘤的手术定位。将亚甲蓝加入林格液中,由周围静脉滴注2.5～5mg/kg。注药后0.5～1h胰腺染成淡蓝色,而胰岛素瘤染成深蓝色或紫褐色。因此,对胰岛素瘤手术极有帮助。 2 亚甲蓝用于高选择性迷走神经切断术的诊断。将无色亚甲蓝涂于手术部位,由于亚甲蓝有亲神经组织性,而神经组织较其它组织氧化代谢快,所以迷走神经很快变成蓝色。从而使高选择性迷走神经切断术更为确切、有效。无色亚甲蓝灭菌溶液的制备方法:先将2.0g亚甲蓝溶于400ml注射用水中,再加入碳酸氢钠8.5g搅拌使之溶解。而后分次加入维生素C
Methylene blue is a chemically active redox agent. In the past for the treatment and rescue of methemoglobinemia, clinical application in surgery is rather limited, in recent years conducted a more extensive study and made gratifying progress, are introduced below. 1 methylene blue staining for the localization of insulinoma surgery. Methylene blue will be added to Ringer’s solution, by intravenous infusion of 2.5 ~ 5mg / kg. After injection of 0.5 ~ 1h pancreatic stained light blue, while insulinoma stained dark blue or purple brown. Therefore, very helpful for insulinoma surgery. 2 methylene blue for the diagnosis of highly selective vagotomy. The colorless methylene blue applied to the surgical site, because methylene blue has a neuronal organization, and nerve tissue oxidation metabolism than other tissues quickly, so the vagus nerve quickly turns blue. So that highly selective vagotomy is more accurate and effective. Preparation of colorless methylene blue sterilization solution: First 2.0g methylene blue dissolved in 400ml water for injection, then add sodium bicarbonate 8.5g stirring to dissolve. And then divided into vitamin C