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目的探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者病情严重程度与血压增高的关系。方法用多导睡眠图监测仪进行整夜睡眠监测134例OSAHS受试者,同时测量睡前、醒后血压。结果OSAHS患者的血压水平明显高于对照组;重度OSAHS患者亦血压高于轻中度组。104例OSAHS患者的高血压发病率为51.9%;其中,轻中度为37.9%,重度为69.6%。OSAHS组醒后血压较睡前血压有增高。15例中重度OSAHS合并高血压患者经自动调节持续正压通气(Auto-CPAP)治疗1个月后,血压较前明显下降。结论OSAHS是引起或加重高血压的病因之一。高血压的发生率和血压增高的程度随着OSAHS病情的加重而增高。经Auto-CPAP治疗1个月后可明显降低血压。
Objective To investigate the relationship between the severity of hypertension and the severity of obstructive sleep apnea-hypopnea syndrome (OSAHS). Methods A total of 134 OSAHS subjects undergoing nighttime sleep monitoring were monitored with polysomnography, and blood pressure was measured before going to sleep and then awake. Results The blood pressure of patients with OSAHS was significantly higher than that of the control group. The patients with severe OSAHS also had higher blood pressure than those of the mild and moderate groups. The incidence of hypertension in 104 OSAHS patients was 51.9%, with mild to moderate 37.9% and severe 69.6%. OSAHS group waking up after blood pressure than before sleep blood pressure increased. Fifteen patients with moderate-to-severe OSAHS complicated with hypertension underwent auto-CPAP for one month after treatment, and their blood pressure decreased significantly compared with that before. Conclusion OSAHS is one of the causes of hypertension. Hypertension and blood pressure increased with OSAHS increased severity of the disease. After 1 month of Auto-CPAP treatment can significantly lower blood pressure.