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本文旨在研究在棉和亚麻粉尘的作用下,棉尘症和慢性喘息性支气管炎患者中性白细胞与淋巴细胞的相关反应中组胺作用的机理。测定了血清中组胺含量,淋巴细胞和中性白细胞亚群的受体/组胺分布(玫瑰花环形成的双倍和三倍反应),及在白细胞移动抑制反应中对淋巴细胞—中性白细胞结合组胺的模拟作用的测定,结果显示在棉尘作用下,有中性白细胞和补体系统的参与,而淋巴细胞很可能未包括在此过程中。亚麻粉尘作用的组胺反应没有差异,淋巴细胞和中性白细胞反应性在棉尘症患者中不超过正常水平。
The purpose of this paper is to study the mechanism of histamine action in the correlation between neutrophils and lymphocytes in cotton dust and chronic asthmatic bronchitis under the action of cotton and linen dust. Histamine levels in the serum, receptor / histamine distribution of lymphocytes and neutrophil subpopulations (double and triple reaction of rosette formation), and serum levels of histamine were measured in lymphocyte-neutrophilic leukocyte Combined with histamine simulation, the results show that the role of cotton dust in the neutrophil and complement system involvement, and lymphocytes is likely not included in the process. There was no difference in the histamine response to flax dust, and lymphocyte and neutrophil reactivity did not exceed normal levels in patients with cotton dust disease.