论文部分内容阅读
目的 探讨新生儿缺氧缺血性脑病 (HIE)合并低钠血症的诊治。方法 对 1999年 1月至 2 0 0 1年 12月我院收治的新生儿缺氧缺血性脑病病人中血钠 <130mmol/L诊断为低钠血症并给予治疗 ,共 10 5例。以积极治疗原发病为基础 ,在吸氧、保护脑代谢等综合治疗的同时 ,对轻度低钠血症病人给予限水、利尿等治疗 ;对于中、重度低钠血症病人按 3 %氯化钠 12ml/kg提高 10mmol/L血钠计算 ,经静脉滴注 3%氯化钠或生理盐水 ,无胃功能障碍者分次口服生理盐水提高血钠。结果 轻度低钠血症 42例 ,占 40 0 % ,中度 5 2例 ,占 49 5 2 % ,重度 11例 ,占 10 48%。痊愈 83例 ,治愈率 79 0 5 % ,死亡 14例 ,病死率 13 33%。因病情危重自动出院 8例 ,占 7 6 2 %。结论 早期诊断低钠血症 ,及时治疗 ,降低HIE病死率。
Objective To investigate the diagnosis and treatment of neonatal hypoxic-ischemic encephalopathy (HIE) complicated with hyponatremia. Methods From January 1999 to December 2001 in our hospital admitted to neonatal hypoxic-ischemic encephalopathy in patients with serum sodium <130mmol / L diagnosis of hyponatremia and give treatment, a total of 105 cases. To active treatment of primary disease as the basis, in oxygen, to protect brain metabolism and other comprehensive treatment, mild hyponatremia patients given water, diuretic and other treatment; for moderate and severe hyponatremia patients by 3% Sodium chloride 12ml / kg increased 10mmol / L of sodium, calculated by intravenous infusion of 3% sodium chloride or saline, no gastric dysfunction, sub-grade saline to increase serum sodium. Results Mild hyponatremia in 42 cases, 40 0%, moderate in 52 cases, accounting for 49 5 2%, severe in 11 cases, accounting for 10 48%. 83 cases were cured, the cure rate was 79 0 5%, 14 died and the case fatality rate was 13 33%. Eight patients were discharged automatically due to the serious condition, accounting for 76.2%. Conclusion Early diagnosis of hyponatremia, timely treatment, reduce the mortality of HIE.