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代谢性酸中毒(MA)是慢性肾衰竭患者常出现的临床表现,可能与蛋白质-热能营养不良(PEM)和炎症有关,后两者合称为营养不良-炎症反应综合征(M ICS)。酸血症是引起慢性肾衰竭患者预后不良和死亡的重要原因。然而新近许多流行病学的研究显示慢性肾衰竭患者MA的“逆流行病学”现象。本文就MA与慢性肾衰竭患者M ICS关系的研究进展作一综述。
Metabolic acidosis (MA) is a common clinical manifestation of patients with chronic renal failure and may be related to protein-heat malnutrition (PEM) and inflammation, the latter two being malnutrition-inflammatory response syndrome (M ICS). Acidosis is an important cause of poor prognosis and death in patients with chronic renal failure. However, many recent epidemiological studies have shown “reverse-epidemiology” of MA in patients with chronic renal failure. This article reviews the research progress of M ICS in patients with chronic renal failure.