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O-(2,4-二硝基苯基)羟胺(1)是有机合成中一个优良的胺化试剂,可用于各类含仲氮及负碳离子化合物的胺化反应。用1进行胺化不仅操作简便,而且适合于其分子中存在其它对亚硝化或随后还原时有影响的化合物引入氨基。例如抗菌剂氨氟沙星(ami-
O- (2,4-Dinitrophenyl) hydroxylamine (1) is an excellent amination reagent in organic synthesis and can be used in the amination of various secondary and secondary carbanion compounds. Amination with 1 is not only easy to handle, but also suitable for the introduction of amino groups in other molecules in the molecule that have an effect on the nitrosation or subsequent reduction. For example, the antibacterial agent ami-