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经结肠镜筛查发现一个或以上的腺瘤(腺瘤检出率)是检查质量的推荐标准,然而,腺瘤检出率与患者后续结直肠癌发病风险和死亡风险之间所存在的联系如何,目前还不甚明了。美国Kaiser Permanente的Corley等应用整合健康传递组织中的数据,评估了腺瘤检出率和在进行结肠镜检查后第6个月至第10年间结直肠癌发病风险以及与肿瘤相关的死亡风险。他们采用Cox回归模型,将预计的特异风险根据受试者的人口学特征、结肠镜检查指征和受试者的并存情况进行调整。评估了314872例结肠镜检查结果,这些检查由136名胃肠病学家完成,腺瘤的检出率从7.4%~52.5%不等。随访
Colonoscopy screening for one or more adenomas (adenoma detection rate) is the recommended standard of quality, however, the association between adenoma detection rates and subsequent patient risk of developing colorectal cancer and the risk of death How, it is not clear yet. The Corley et al. Application by Kaiser Permanente in the United States integrated data from the health delivery organization to assess adenoma detection rates and the risk of developing colorectal cancer and the risk of cancer-related death from the 6th month to the 10th year after colonoscopy. They used a Cox regression model to adjust the projected specific risk to the subject’s demographic characteristics, colonoscopy indications, and co-morbidities. A total of 314,872 colonoscopy results were evaluated. These tests were performed by 136 gastroenterologists with adenoma detection rates ranging from 7.4% to 52.5%. Follow-up